Alternative splicing in human, mouse and rat

and implications for phylogenetic study

from Modrek and Lee (2003)

What is splicing?

Splicing is the process that occurs after transcription of DNA, and by which discontinous coding regions (exons) are assembled into a single mature mRNA.

http://departments.oxy.edu/biology/Stillman/bi221/111300/processing_of_hnrnas.htm

http://www.nobel.se/medicine/educational/dna/b/splicing/

lampbrush chromosome, detailing hnRNP (red), DNA (white)

http://departments.oxy.edu/biology/Stillman/bi221/111300/processing_of_hnrnas.htm

Type I, Type II self splicing introns, are found in eubacteria, archaebacteria and eukaryotes

Spliceosomal introns are found only in eukaryotes

from Tree of Life website

http://departments.oxy.edu/biology/Stillman/bi221/111300/processing_of_hnrnas.htm