• Signal transduction, the basic problem addressed:
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•How to convert
external receptor binding event -> across membrane -> into intracellular biochemical event
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•Common Properties:
signal amplification, multiple levels with controls at each level
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•For lasting changes
the ultimate destination is the nucleus and regulation of transcription
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•Results of signal
transduction: changes in cytoskeleton, rearrangement of secretory apparatus, progression of the
cell cycle, etc…